Caring for critically ill patients requires professional training, but also great wisdom for life, preceded by deep ethical and moral reflection. In palliative medicine, the interest in ethical principles is enormous because of the specific problems that arise in caring for patients at the end of life. It is important to take care of the patient's subjectivity, his dignity, proper communication and truth-telling. The notion of respecting autonomy includes the patient's right to make informed decisions, information about diagnosis, prognosis and treatment. From an ethical point of view, a difficult problem is the concept of persistent therapy, the consequence of which should be the decision to abandon all ineffective or purposeless measures, since they prolong dying and involve excessive suffering for the patient. A major ethical dilemma is the use of the principle of double effect as applied in palliative sedation. It is part of therapy and its aim is to relieve suffering. The principle of doing good is linked to issues of value and quality of life. Palliative care combines aspects of medical, psychological, social and spiritual support, and treats dying as a natural process, accepting its inevitability. The essence of the intervention is to strive for the highest quality of the patient's last period of life. It is not the duty of the doctor to fight death at all costs. Staff caring for seriously ill patients are often obliged to resolve many moral dilemmas. Ethics in end-of-life medicine aims to uphold the humanistic dimension of the art of medicine